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Article

Imprinted X inactivation and reprogramming in the preimplantation mouse embryo.

Human molecular genetics - 15 Apr 2005

Sado Takashi, Ferguson-Smith Anne C

Abstract excerpt

X chromosome inactivation is a developmentally regulated process that causes one of the two X chromosomes in normal female mammals to become transcriptionally silenced, thus equalizing the expression of X-linked genes between the sexes. Such dosage compensation depends upon dynamic genetic and epigenetic events occurring very early in development. X inactivation is controlled by an X inactivation centre that is...

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PMID: 15809274
DOI: 10.1093/hmg/ddi117

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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