Article
Functional monoamine oxidase B gene intron 13 polymorphism predicts putaminal dopamine turnover in de novo Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society - 1 Sept 2018
Löhle Matthias, Mangone Graziella, Wolz Martin, Beuthien-Baumann Bettina, Oehme Liane, van den Hoff Jörg, Kotzerke Jörg, Reichmann Heinz, Corvol Jean-Christophe, Storch Alexander
Abstract excerpt
OBJECTIVE: The objective of this study was to evaluate the effects of common functional polymorphisms in genes involved in dopamine metabolism on striatal dopamine turnover in de novo Parkinson's disease (PD). METHODS: This was an observer-blinded cohort study investigating effects of common functional polymorphisms in dopa decarboxylase (DDC, rs921451), monoamine oxidase B (MAOB; rs1799836),...
Read the complete abstract on PubMed