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Article

Influence of single nucleotide polymorphisms in COMT, MAO-A and BDNF genes on dyskinesias and levodopa use in Parkinson's disease.

Neuro-degenerative diseases - 1 Jan 2014

Cheshire Perdita, Bertram Kelly, Ling Helen, O'Sullivan Sean S, Halliday Glenda, McLean Catriona, Bras Jose, Foltynie Tom, Storey Elsdon, Williams David R

Abstract excerpt

BACKGROUND: Clinical heterogeneity in the development of levodopa-induced dyskinesias (LID) suggests endogenous factors play a significant role in determining their overall prevalence. OBJECTIVE: We hypothesised that single nucleotide polymorphisms (SNPs) in specific genes may result in a clinical phenotype conducive to an increased risk of LID. METHODS: We examined the influence of SNPs in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Catechol O-Methyltransferase

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Source

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Identifiers

PMID: 24008922
DOI: 10.1159/000351097
PMCID: PMC4194629

Genes

COMT
BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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