Article
Quantitative dopamine transporter imaging assessment in Parkinson's disease patients carrying GBA gene mutations compared with idiopathic PD patients: A case-control study.
Brain and behavior - 1 Jul 2023
Grisanti Sara, Fraternali Alessandro, Cavallieri Francesco, Fioravanti Valentina, Casali Massimiliano, Toschi Giulia, Ferri Laura, Sabadini Rossella, Zedde Marialuisa, Salomone Gaetano, Napoli Manuela, Pascarella Rosario, Ferrari Valeria, Scarano Maria, Biagini Giuseppe, Scaglioni Augusto, Moro Elena, Versari Annibale, Valzania Franco
Abstract excerpt
BACKGROUND: Genetic risk factors impact around 15% of Parkinson's disease (PD) patients and at least 23 variants have been identified including Glucocerebrosidase (GBA) gene variants. Using different clinical and instrumental qualitative-based data, various studies have been published on GBA-PD cohorts which suggested possible differences in dopaminergic nigrostriatal denervation pattern, particularly in caudate...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.