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Case‐Control study of dopamine transporter‐1, monoamine oxidase‐B, and catechol‐<i>O</i>‐methyl transferase polymorphisms in Parkinson's disease

1 Nov 2002

Abstract excerpt

We investigated the association of Parkinson's disease (PD) with dopamine transporter-1 (DAT1), monoamine oxidase-B (MAO-B), and catechol-O-methyltransferase (COMT) gene polymorphisms. Overall, we observed no significant association of PD with the DAT1-3'-variable numbers of tandem repeats, the MAO-B-(GT)(n), and the COMT-Val108Met gene polymorphisms in a sample of 319 unrelated PD cases and 196 control subjects....

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PMID: 12465073
DOI: 10.1002/mds.10268

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