Article
Omega-3 Fatty Acids Prevent Early Pancreatic Carcinogenesis via Repression of the AKT Pathway.
Nutrients - 12 Sept 2018
Ding Yongzeng, Mullapudi Bhargava, Torres Carolina, Mascariñas Emman, Mancinelli Georgina, Diaz Andrew M, McKinney Ronald, Barron Morgan, Schultz Michelle, Heiferman Michael, Wojtanek Mireille, Adrian Kevin, DeCant Brian, Rao Sambasiva, Ouellette Michel, Tsao Ming-Sound, Bentrem David J, Grippo Paul J
Abstract excerpt
Pancreatic cancer remains a daunting foe despite a vast number of accumulating molecular analyses regarding the mutation and expression status of a variety of genes. Indeed, most pancreatic cancer cases uniformly present with a mutation in the KRAS allele leading to enhanced RAS activation. Yet our understanding of the many epigenetic/environmental factors contributing to disease incidence and progression is...
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