Article
Antigenic drift of viruses within a host: a finite site model with demographic stochasticity.
Journal of molecular evolution - 1 Sept 2000
Sasaki A, Haraguchi Y
Abstract excerpt
We theoretically study the antigenic drift of viruses within an infected host, as observed in human immunodeficiency virus (HIV) and equine infectious anemia virus (EIAV) infections, assuming that a finite number of antigen-determining sites at the viral envelop gene are responsible for the specific immune response. The pattern of antigen evolution becomes more complex than that predicted from the previous...
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