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Article

Phenotypic differences in viral immune escape explained by linking within-host dynamics to host-population immunity.

Journal of theoretical biology - 21 Aug 2010

Pepin K M, Volkov I, Banavar J R, Wilke C O, Grenfell B T

Abstract excerpt

Viruses that do not cause life-long immunity persist by evolving rapidly in response to prevailing host immunity. The immune-escape mutants emerge frequently, displacing or co-circulating with native strains even though mutations conferring immune evasion are often detrimental to viral replication. The epidemiological dynamics of immune-escape in acute-infection viruses with high transmissibility have been...

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Identifiers

PMID: 20570681
DOI: 10.1016/j.jtbi.2010.05.036
PMCID: PMC4537168

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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