Article

Impact of vaccination on the speed of antigenic evolution

2026-03-11

Abstract excerpt

Rapidly evolving pathogens can escape antibody-mediated immunity, leading to recurrent epidemics. Vaccination is a key intervention to reduce infections and severe disease, yet concerns remain that it may accelerate antigenic evolution, potentially undermining long-term vaccine effectiveness. We developed a multi-strain mathematical model, parameterized for a rapidly evolving pathogen, to systematically explore ho...

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Literature Corpus work: 286beaf2-8c7a-5d32-8a8e-4fb6e563c527
DOI: 10.64898/2026.03.10.26347605

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