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Article

CCBE1 is required for coronary vessel development and proper coronary artery stem formation in the mouse heart

11 Sept 2018

Abstract excerpt

BACKGROUND: Proper coronary vasculature development is essential for late-embryonic and adult heart function. The developmental regulation of coronary embryogenesis is complex and includes the coordinated activity of multiple signaling pathways. CCBE1 plays an important role during lymphangiogenesis, enhancing VEGF-C signaling, which is also required for coronary vasculature formation. However, whether CCBE1...

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PMID: 30204931
DOI: 10.1002/dvdy.24670

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