Article

Endocardium-to-coronary artery differentiation during heart development and regeneration involves sequential roles of Bmp2 and Cxcl12/Cxcr4

2021-10-26

Abstract excerpt

<h4>ABSTRACT</h4> Regenerating coronary blood vessels has the potential to ameliorate ischemic heart disease, yet there is currently no method of stimulating clinically effective cardiac angiogenesisis. Endocardial cells— a particularly plastic cell type during development—line the heart lumen and are natural coronary vessel progenitors. Their intrinsic angiogenic potential is lost in adults, but studying the end...

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Literature Corpus work: 028e9dc5-0d57-5207-bffb-80d7a0b5cde7
DOI: 10.1101/2021.10.25.465773

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