Article
Coronary Artery Development: Origin, Malformations, and Translational Vascular Reparative Therapy.
Journal of cardiovascular pharmacology and therapeutics - 1 Jul 2018
Ramai Daryl, Lai Jonathan, Monzidelis Constantine, Reddy Sarath
Abstract excerpt
After thickening of the cardiac chamber walls during embryogenesis, oxygen and nutrients can no longer be adequately supplied to cardiac cells via passive diffusion; therefore, a primitive vascular network develops to supply these vital structures. This plexus further matures into coronary arteries and veins, which ensures continued development of the heart. Various models have been proposed to account for the...
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