Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alternative Progenitor Cells Compensate to Rebuild the Coronary Vasculature in Elabela- and Apj-Deficient Hearts.

Developmental cell - 25 Sept 2017

Sharma Bikram, Ho Lena, Ford Gretchen Hazel, Chen Heidi I, Goldstone Andrew B, Woo Y Joseph, Quertermous Thomas, Reversade Bruno, Red-Horse Kristy

Abstract excerpt

Organogenesis during embryonic development occurs through the differentiation of progenitor cells. This process is extraordinarily accurate, but the mechanisms ensuring high fidelity are poorly understood. Coronary vessels of the mouse heart derive from at least two progenitor pools, the sinus venosus and endocardium. We find that the ELABELA (ELA)-APJ signaling axis is only required for sinus venosus-derived...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coronary Vessels
Share to Endocardium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HMGB Proteins

Share to Hypoxia

Share to Neovascularization, Physiologic

Share to Peptide Hormones

Share to Receptors, G-Protein-Coupled

Share to SOXF Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 28890073
DOI: 10.1016/j.devcel.2017.08.008
PMCID: PMC5895086

Genes

SOX17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alternative Progenitor Cells Compensate to Rebuild the Coronary Vasculature in Elabela- and Apj-Deficient Hearts.PMID 28890073Read ↗

CCBE1 is required for coronary vessel development and proper coronary artery stem formation in the mouse heartSemantic proximity Read ↗

Wt1+/Itga4+ progenitors drive epicardial-derived cell expansion via non-canonical Wnt signallingSemantic proximity Read ↗

Coronary blood vessels from distinct origins converge to equivalent states during mouse and human developmentSemantic proximity Read ↗

Molecular mechanisms controlling the coupled development of myocardium and coronary vasculature.Semantic proximity Read ↗

Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis.Semantic proximity Read ↗

Endocardium-to-coronary artery differentiation during heart development and regeneration involves sequential roles of Bmp2 and Cxcl12/Cxcr4Semantic proximity Read ↗

The formation of the embryonic mouse heartSemantic proximity Read ↗

Pbx4 limits heart size and fosters arch artery formation by partitioning second heart field progenitors and restricting proliferationSemantic proximity Read ↗

The Epicardium in the Embryonic and Adult ZebrafishSemantic proximity Read ↗

Zebrafish arterial valve development occurs through direct differentiation of second heart field progenitors.Semantic proximity Read ↗

Ventricular, atrial and outflow tract heart progenitors arise from spatially and molecularly distinct regions of the primitive streakSemantic proximity Read ↗

Wdpcp promotes epicardial EMT and epicardium-derived cell migration to facilitate coronary artery remodeling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.