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Article

Extracardiac septum transversum/proepicardial endothelial cells pattern embryonic coronary arterio-venous connections.

Proceedings of the National Academy of Sciences of the United States of America - 19 Jan 2016

Cano Elena, Carmona Rita, Ruiz-Villalba Adrián, Rojas Anabel, Chau You-Ying, Wagner Kay D, Wagner Nicole, Hastie Nicholas D, Muñoz-Chápuli Ramón, Pérez-Pomares José M

Abstract excerpt

Recent reports suggest that mammalian embryonic coronary endothelium (CoE) originates from the sinus venosus and ventricular endocardium. However, the contribution of extracardiac cells to CoE is thought to be minor and nonsignificant for coronary formation. Using classic (Wt1(Cre)) and previously undescribed (G2-Gata4(Cre)) transgenic mouse models for the study of coronary vascular development, we show that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26739565
DOI: 10.1073/pnas.1509834113
PMCID: PMC4725486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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