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Article

Improved Chemical-Genetic Fluorescent Markers for Live Cell Microscopy.

Biochemistry - 2 Oct 2018

Tebo Alison G, Pimenta Frederico M, Zhang Yu, Gautier Arnaud

Abstract excerpt

Inducible chemical-genetic fluorescent markers are promising tools for live cell imaging requiring high spatiotemporal resolution and low background fluorescence. The fluorescence-activating and absorption shifting tag (FAST) was recently developed to form fluorescent molecular complexes with a family of small, synthetic fluorogenic chromophores (so-called fluorogens). Here, we use rational design to modify the...

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PMID: 30204425
DOI: 10.1021/acs.biochem.8b00649

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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