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Structure-guided rational design of red fluorescent proteins: towards designer genetically-encoded fluorophores.

Current opinion in structural biology - 1 Aug 2017

Eason Matthew G, Damry Adam M, Chica Roberto A

Abstract excerpt

Red fluorescent proteins (RFPs) have become an integral part of modern biological research due to their longer excitation and emission wavelengths. Protein engineering efforts have improved many key properties of RFPs for their practical use in imaging. Even so, continued engineering is required to overcome the shortcomings of the red chromophore and create RFPs with photophysical properties rivalling those of...

Topics

Light
Luminescent Proteins
Mutation
Protein Engineering
Protein Multimerization
Protein Stability
Red Fluorescent Protein

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 28038355
DOI: 10.1016/j.sbi.2016.12.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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