Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Mutations in B-Acute Lymphoblastic Leukemia Among African American and European American Children.

Clinical lymphoma, myeloma & leukemia - 1 Dec 2018

Reddy Amit, Espinoza Ingrid, Cole Dana, Schallheim Jason, Poosarla Teja, Bhanat Eldrin, Zhou Yunyun, Zabaleta Jovanny, Megason Gail, Gomez Christian R

Abstract excerpt

BACKGROUND: The survival of patients with B-acute lymphoblastic leukemia (B-ALL) is significantly lower in African American (AA) children compared with European American children (EA). Here, we present a whole exome sequencing (WES) study showing race-specific genetic variations that may play a role on the disparate outcomes among AA and EA children with B-ALL. PATIENTS AND METHODS: Five AA and 15 EA patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biopsy
Share to Black or African American

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bone Marrow

Share to Disease Management

Share to Germ-Line Mutation

Share to Population Surveillance

Share to Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

Share to Whole Genome Sequencing

Source

Identifiers

PMID: 30181103
DOI: 10.1016/j.clml.2018.08.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Mutations in B-Acute Lymphoblastic Leukemia Among African American and European American Children.PMID 30181103Read ↗

Genome-wide association study of childhood B-cell acute lymphoblastic leukemia reveals novel African ancestry-specific susceptibility loci.Semantic proximity Read ↗

Genetic subtypes of B-cell acute lymphoblastic leukemia in adultsSemantic proximity Read ↗

Molecular genetics of B-precursor acute lymphoblastic leukemia.Semantic proximity Read ↗

Oncogenic lesions and molecular subtypes in adults with B-cell acute lymphoblastic leukemia.Semantic proximity Read ↗

Whole genome sequencing provides comprehensive genetic testing in childhood B-cell acute lymphoblastic leukaemiaSemantic proximity Read ↗

Genomic profiling of Mexican patients with B-cell precursor acute lymphoblastic leukemia reveals clinically significant somatic and potential germline variants.Semantic proximity Read ↗

Diagnostic utility of whole genome sequencing in adults with B-other acute lymphoblastic leukemia.Semantic proximity Read ↗

Family-based exome-wide association study of childhood acute lymphoblastic leukemia among Hispanics confirms role of ARID5B in susceptibility.Semantic proximity Read ↗

Impact of Genetic Ancestry on T-cell Acute Lymphoblastic Leukemia OutcomesSemantic proximity Read ↗

Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group.Semantic proximity Read ↗

Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia.Semantic proximity Read ↗

Genomic ancestry and somatic alterations correlate with age at diagnosis in Hispanic children with B-cell acute lymphoblastic leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.