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Article

Oncogenic lesions and molecular subtypes in adults with B-cell acute lymphoblastic leukemia.

Cancer science - 1 Jan 2023

Yasuda Takahiko, Sanada Masashi, Tsuzuki Shinobu, Hayakawa Fumihiko

Abstract excerpt

B-cell acute lymphoblastic leukemia (B-ALL), a genetically heterogeneous disease, is classified into different molecular subtypes that are defined by recurrent gene rearrangements, gross chromosomal abnormalities, or specific gene mutations. Cells with these genetic alterations acquire a leukemia-initiating ability and show unique expression profiles. The distribution of B-ALL molecular subtypes is greatly...

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Identifiers

PMID: 36106363
DOI: 10.1111/cas.15583
PMCID: PMC9807527

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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