Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular genetics of B-precursor acute lymphoblastic leukemia.

The Journal of clinical investigation - 1 Oct 2012

Mullighan Charles G

Abstract excerpt

B-precursor acute lymphoblastic leukemia (B-ALL) is the most common childhood tumor and the leading cause of cancer-related death in children and young adults. The majority of B-ALL cases are aneuploid or harbor recurring structural chromosomal rearrangements that are important initiating events in leukemogenesis but are insufficient to explain the biology and heterogeneity of disease. Recent studies have used...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B-Lymphocytes
Share to Cell Lineage
Share to Clone Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hematopoietic Stem Cells

Share to Neoplasm Proteins

Share to Oncogene Proteins, Fusion

Share to Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

Share to Translocation, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 23023711
DOI: 10.1172/JCI61203
PMCID: PMC3461902

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular genetics of B-precursor acute lymphoblastic leukemia.PMID 23023711Read ↗

Genomic profiling of B-progenitor acute lymphoblastic leukemia.Semantic proximity Read ↗

Genetic subtypes of B-cell acute lymphoblastic leukemia in adultsSemantic proximity Read ↗

Advances in the Biology of Acute Lymphoblastic Leukemia—From Genomics to the ClinicSemantic proximity Read ↗

Oncogenic lesions and molecular subtypes in adults with B-cell acute lymphoblastic leukemia.Semantic proximity Read ↗

Genetic Biomarkers and Their Clinical Implications in B-Cell Acute Lymphoblastic Leukemia in Children.Semantic proximity Read ↗

Genomic characterization of childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

Molecular genetics of acute lymphoblastic leukemia.Semantic proximity Read ↗

B‐cell acute lymphoblastic leukaemia: recent discoveries in molecular pathology, their prognostic significance, and a review of the current classificationSemantic proximity Read ↗

Genetic abnormalities associated with acute lymphoblastic leukemia.Semantic proximity Read ↗

Diagnosis of acute lymphoblastic leukaemia: an overview of the current genomic classification, diagnostic approaches, and future directionsSemantic proximity Read ↗

Childhood acute lymphoblastic leukemia: Integrating genomics into therapy.Semantic proximity Read ↗

The Biology of B-Progenitor Acute Lymphoblastic Leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.