Article
Risk-reducing salpingo-oophorectomy in BRCA1 and BRCA2 mutation carriers.
Archives of gynecology and obstetrics - 1 Mar 2011
Rhiem Kerstin, Foth Dolores, Wappenschmidt Barbara, Gevensleben Heidrun, Büttner Reinhard, Ulrich Uwe, Schmutzler Rita K
Abstract excerpt
BACKGROUND: Risk-reducing salpingo-oophorectomy (RRSO) is often recommended to carriers of deleterious breast cancer gene 1/2 (BRCA1/2) mutations in order to reduce their breast cancer risk by 50% and their ovarian cancer risk by approximately 95%. To evaluate the acceptance, timing, histopathology findings and follow-up results we retrospectively analyzed a cohort of BRCA1/2 mutation carriers who underwent...
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