Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Risk-reducing strategies for women carrying BRCA1/2 mutations with a focus on prophylactic surgery.

BMC women's health - 20 Oct 2010

Salhab Mohamed, Bismohun Selina, Mokbel Kefah

Abstract excerpt

BACKGROUND: Women who have inherited mutations in the BRCA1 or BRCA2 genes have substantially elevated risks of breast and ovarian cancer. Mutation carriers have various options, including extensive and regular surveillance, chemoprevention and risk-reducing surgery. The aim of this review is to provide an up-to-date analysis and to subsequently summarise the available literature in relation to risk-reducing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Genes, BRCA1
Share to Genes, BRCA2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mastectomy

Share to Mutation

Share to Ovarian Neoplasms

Share to Ovariectomy

Source

Open in PubMed Open full text

Identifiers

PMID: 20961453
DOI: 10.1186/1472-6874-10-28
PMCID: PMC2987888

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Risk-reducing strategies for women carrying BRCA1/2 mutations with a focus on prophylactic surgery.PMID 20961453Read ↗

Risk reduction and survival benefit of prophylactic surgery in BRCA mutation carriers, a systematic review.Semantic proximity Read ↗

Risk-reducing salpingo-oophorectomy in BRCA1 and BRCA2 mutated patients: An evidence-based approach on what women should know.Semantic proximity Read ↗

Risk-reducing bilateral salpingo-oophorectomy in women with BRCA1 or BRCA2 mutations.Semantic proximity Read ↗

Risk-reducing surgery on the uterine adnexa: timing and type of surgical treatment, and pathology report.Semantic proximity Read ↗

Prophylactic salpingectomy with delayed oophorectomy as a two-staged alternative for primary prevention of ovarian cancer in BRCA1/2 mutation carriers: women's point of view.Semantic proximity Read ↗

Risk-Reducing Strategies for Ovarian Cancer in BRCA Mutation Carriers: A Balancing Act.Semantic proximity Read ↗

Risk-reducing salpingo-oophorectomy and breast cancer risk in BRCA1 or BRCA2 mutation carriers: A systematic review and meta-analysis.Semantic proximity Read ↗

Management options after prophylactic surgeries in women with BRCA mutations: a review.Semantic proximity Read ↗

Breast Cancer Risk Reduction Decisions of the BRCA-Positive Patient: An Observational Study at a Single Institution.Semantic proximity Read ↗

The clinical management of BRCA1 and BRCA2 mutation carriers.Semantic proximity Read ↗

Hereditary Women's Cancer: Management and Risk-Reducing Surgery.Semantic proximity Read ↗

Management updates for women with a BRCA1 or BRCA2 mutation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.