Article
Risk-reducing salpingo-oophorectomy: a meta-analysis on impact on ovarian cancer risk and all cause mortality in BRCA 1 and BRCA 2 mutation carriers.
BMC women's health - 12 Dec 2014
Marchetti Claudia, De Felice Francesca, Palaia Innocenza, Perniola Giorgia, Musella Angela, Musio Daniela, Muzii Ludovico, Tombolini Vincenzo, Panici Pierluigi Benedetti
Abstract excerpt
BACKGROUND: Women with BRCA1 and BRCA2 mutation carriers are at substantially elevated risk of developing ovarian cancer. The aim of the meta-analysis is to clarify the role of risk-reducing salpingo-oophorectomy (RRSO) to reduce ovarian cancer risk and mortality in women with BRCA 1 and BRCA 2 mutation carriers. METHODS: Pubmed, Medline and Scopus were searched to select English-language articles. Two...
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