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Risk-reducing salpingo-oophorectomy and breast cancer risk in BRCA1 or BRCA2 mutation carriers: A systematic review and meta-analysis.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Jun 2022

Wang Yizi, Song Zixuan, Zhang Shitai, Wang Xiaoying, Li Peiwen

Abstract excerpt

AIM: BRCA mutation carriers have a high lifetime risk of developing breast cancer (BC) and ovarian cancer (OC). Risk-reducing salpingo-oophorectomy (RRSO) has been shown to reduce OC risk. This meta-analysis was aim to analyze the effect of RRSO on the BC risk among BRCA1/2 mutation carriers. METHODS: Embase, PubMed, Web of Science, and Cochrane databases were searched for all studies investigating the effect of...

Topics

BRCA1 Protein
BRCA2 Protein
Breast Neoplasms
Female
Genetic Predisposition to Disease
Humans
Mutation
Observational Studies as Topic
Ovarian Neoplasms
Ovariectomy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Risk Reduction Behavior

Salpingo-oophorectomy

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Identifiers

PMID: 35216860
DOI: 10.1016/j.ejso.2022.02.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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