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Article

Risk-reducing salpingo-oophorectomy and breast cancer risk in BRCA1 or BRCA2 mutation carriers: A systematic review and meta-analysis.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Jun 2022

Wang Yizi, Song Zixuan, Zhang Shitai, Wang Xiaoying, Li Peiwen

Abstract excerpt

AIM: BRCA mutation carriers have a high lifetime risk of developing breast cancer (BC) and ovarian cancer (OC). Risk-reducing salpingo-oophorectomy (RRSO) has been shown to reduce OC risk. This meta-analysis was aim to analyze the effect of RRSO on the BC risk among BRCA1/2 mutation carriers. METHODS: Embase, PubMed, Web of Science, and Cochrane databases were searched for all studies investigating the effect of...

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Identifiers

PMID: 35216860
DOI: 10.1016/j.ejso.2022.02.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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