Article
Risk-Reducing Strategies for Ovarian Cancer in BRCA Mutation Carriers: A Balancing Act.
The oncologist - 1 Apr 2017
Tschernichovsky Roi, Goodman Annekathryn
Abstract excerpt
OBJECTIVE: The objective of this study was to review the role of bilateral salpingo-oophorectomy in BRCA mutation (mBRCA) carriers and alternative interventions in risk reduction of ovarian cancer (OC). MATERIALS AND METHODS: A systematic review using PubMed, MEDLINE, EMBASE, and the Cochrane library was conducted to identify studies of different strategies to prevent OC in mBRCA carriers, including bilateral...
Topics
- BRCA1 Protein
- BRCA2 Protein
- Female
- Heterozygote
- Humans
- Mutation
- Ovarian Neoplasms
- Risk Factors
- Salpingo-oophorectomy
