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Article

Cutaneous permeability barrier function in signal transducer and activator of transcription 6-deficient mice is superior to that in wild-type mice.

Journal of dermatological science - 1 Oct 2018

Zhang Wei, Sakai Takashi, Matsuda-Hirose Haruna, Goto Mizuki, Yamate Tomoko, Hatano Yutaka

Abstract excerpt

BACKGROUND: Th2 cytokines exhibit a variety of inhibitory effects on permeability barrier function via signal transducer and activator of transcription 6 (STAT6). However, the role of STAT6 signaling on the construction and/or homeostasis of permeability barrier function in the physiological state has not been fully assessed. OBJECTIVE: We compared permeability barrier function between Stat6-deficient and...

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Source

Identifiers

PMID: 30098864
DOI: 10.1016/j.jdermsci.2018.07.008

Genes

STAT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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