Article
Dermatitis and aging-related barrier dysfunction in transgenic mice overexpressing an epidermal-targeted claudin 6 tail deletion mutant.
PloS one - 13 Nov 2009
Troy Tammy-Claire, Arabzadeh Azadeh, Larivière Nathalie M K, Enikanolaiye Adebola, Turksen Kursad
Abstract excerpt
The barrier function of the skin protects the mammalian body against infection, dehydration, UV irradiation and temperature fluctuation. Barrier function is reduced with the skin's intrinsic aging process, however the molecular mechanisms involved are unknown. We previously demonstrated that Clau...
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