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Article

Increased Th2 activity and diminished skin barrier function cooperate in allergic skin inflammation

11 Aug 2016

Abstract excerpt

Atopic dermatitis (AD) is a chronic inflammatory skin disease induced by a complex interaction between susceptibility genes encoding skin barrier components and environmental allergen exposure that results in type 2 cytokine production. Although genetic lesions in either component can be risk factors for disease in patients, whether these pathways interact in the development of AD is not clear. To test this, we...

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Share to Allergic Rhinitis and Sensitization
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PMID: 27510401
DOI: 10.1002/eji.201646421

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