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Article

Bifidobacterium adolescentis is intrinsically resistant to antitubercular drugs.

Scientific reports - 9 Aug 2018

Lokesh Dhanashree, Parkesh Raman, Kammara Rajagopal

Abstract excerpt

Multiple mutations in the β subunit of the RNA polymerase (rpoβ) of Mycobacterium tuberculosis (Mtb) are the primary cause of resistance to rifamycin (RIF). In the present study, bifidobacterial rpoβ sequences were analyzed to characterize the mutations that contribute to the development of intrinsic resistance to RIF, isoniazid, streptomycin and pyrazinamide. Sequence variations, which mapped to cassettes 1 and...

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Share to Antitubercular Agents
Share to Drug Resistance, Multiple, Bacterial
Share to Isoniazid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30093677
DOI: 10.1038/s41598-018-30429-2
PMCID: PMC6085307

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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