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Mechanisms and detection methods of Mycobacterium tuberculosis rifampicin resistance: The phenomenon of drug resistance is complex.

Tuberculosis (Edinburgh, Scotland) - 1 May 2021

Xu Ge, Liu Hangchi, Jia Xudong, Wang Xiaomin, Xu Peng

Abstract excerpt

Tuberculosis (TB) is an infectious disease that poses a serious threat to human health. Rifampin (RIF) is an important first-line anti-TB drug, and rifampin resistance (RIF-R) is a key factor in formulating treatment regimen and evaluating the prognosis of TB. Compared with other drugs resistance, the RIF-R mechanism of Mycobacterium tuberculosis (M. tuberculosis) is one of the clearest, which is mainly caused by...

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PMID: 33975262
DOI: 10.1016/j.tube.2021.102083

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