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Article

Study of the rifampin monoresistance mechanism in Mycobacterium tuberculosis.

Antimicrobial agents and chemotherapy - 1 Feb 2013

Pang Yu, Lu Jie, Wang Yufeng, Song Yuanyuan, Wang Shengfen, Zhao Yanlin

Abstract excerpt

Rifampin (RIF) susceptibility is a key factor in determining the treatment effectiveness of the standardized treatment regimens. In Mycobacterium tuberculosis, both target gene mutation and the efflux pump play major roles in the resistance to antituberculosis drugs. By eliminating RIF-resistant strains with rpoB mutation, the choice of RIF-monoresistant strains may allow us to identify the RIF-specific efflux...

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Identifiers

PMID: 23208715
DOI: 10.1128/AAC.01024-12
PMCID: PMC3553728

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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