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Rifampin resistance-associated mutations in the RIF resistance-determining region (RRDR) of the rpoB gene of Mycobacterium tuberculosis clinical isolates in Shanghai, China

2019-07-23

Abstract excerpt

<h4>Background: </h4> Resistance to rifampin (RIF) in Mycobacterium tuberculosis infection is associated with mutations in the rpoB gene coding for the beta-subunit of RNA polymerase. The contribution of many individual rpoB mutations to the development and level of RIF resistance remains elusive. Our objective for this study was to investigate the relationship between specific rpoB mutations and the minimum inhib...

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Literature Corpus work
1c58f0f6-1532-595a-a346-e07b57354db1
DOI
10.21203/rs.2.11840/v1
Open publication

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Rifampin resistance-associated mutations in the RIF resistance-determining region (RRDR) of the rpoB gene of Mycobacterium tuberculosis clinical isolates in Shanghai, ChinaDOI 10.21203/rs.2.11840/v1
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