Article
Polymorphisms of p53 promoter and susceptibility to uterine leiomyoma.
Clinical and experimental obstetrics & gynecology - 1 Jan 2000
Ziaei E, Chaleshtori M H, Ziaei A, Dehkordi G B, Pooryamofrad A, Kashani S, Batenipoor M, Miraj S
Abstract excerpt
BACKGROUND: Uterine leiomyomas could be considered as benign tumor of human uterus smooth muscle with unknown etiology and pathophysiology.Furthermore, they are the most common indication of hysterectomy. The tumor suppressor gene p53 has been involved in various malignancies. Mutation in its promoter site may play a role in tumorigenesis of many malignancies including leiomyompa. MATERIALS AND METHODS: For study...
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