A variant of TP53 gene (rs 1625895, 13494g>A) is associated with neoplasm localization in patients with uterine leiomyoma.

doi:10.32471/exp-oncology.2312-8852.vol-43-no-2.16195

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Article

A variant of TP53 gene (rs 1625895, 13494g>A) is associated with neoplasm localization in patients with uterine leiomyoma.

Experimental oncology - 1 Jun 2021

Kornatska A G, Flaksemberg М А, Chubei G V, Trokhymovych О V, Rossokha Z I, Fishchuk L Ye, Medvedieva N L, Vershyhora V O, Gorovenko N G

Abstract excerpt

BACKGROUND: Uterine leiomyoma (UL) is the most common benign neoplasm of the uterus. It is still unknown surely what exactly initiates transformation of the uterine myometrial cells into UL. AIM: To study the effect of the TP53 gene variants on the risk of development and clinical features of UL. MATERIALS AND METHODS: Case-control study was performed using molecular genetic analyses of variants rs1042522...

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PMID: 34190520
DOI: 10.32471/exp-oncology.2312-8852.vol-43-no-2.16195

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