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Article

Age-dependent association of MDM2 promoter polymorphisms and uterine leiomyoma in South-East Iran: A preliminary report.

The journal of obstetrics and gynaecology research - 1 May 2015

Salimi Saeedeh, Hajizadeh Azam, Khodamian Maryam, Pejman Atefeh, Fazeli Kimia, Yaghmaei Minoo

Abstract excerpt

AIM: Murine double minute clone 2 (MDM2) is an important regulator of p53 tumor suppressor protein. Because increased MDM2 expression has been observed in different tumors, its polymorphisms are proposed to be associated with accelerated tumor formation. The aim of this study was to examine the association between T309G (rs2279744) and 40-bp Insertion/deletion (rs3730485) polymorphisms of the MDM2 gene and risk...

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Source

Identifiers

PMID: 25511444
DOI: 10.1111/jog.12625

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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