Article
Polymorphism of the p53 tumor suppressor gene is associated with susceptibility to uterine leiomyoma.
Fertility and sterility - 1 Jul 2005
Denschlag Dominik, Bettendorf Herta, Watermann Dirk, Keck Christoph, Tempfer Clemens, Pietrowski Detlef
Abstract excerpt
OBJECTIVE: To evaluate the association between the presence of uterine leiomyoma and two single nuclear polymorphisms of the p53 tumor suppressor and the angiopoietin-2 (ANGPT2) genes. DESIGN: Prospective case control study. SETTING: Academic research institution. PATIENT(S): One hundred thirty-two women with clinically and surgically diagnosed uterine leiomyomas and 280 controls. INTERVENTION(S): Peripheral...
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