Article
Four novel single nucleotide polymorphisms within the promoter region of p53 gene and their associations with uterine leiomyoma.
Molecular reproduction and development - 1 Jul 2007
Hsieh Yao-Yuan, Wang Jui-Ping, Lin Chich-Sheng
Abstract excerpt
Dysregulated p53 expression has been implicated as a major contributor to numerous tumorigenesis. Single nucleotide polymorphisms (SNPs) within the functional consequence of the novel p53 promoter region remains obscure. Herein, we aimed to establish the extent of genetic variability within the promoter region of p53 gene as well as their association with leiomyoma susceptibility. Women were divided into two...
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