Article
The CYP17 MspA1 polymorphism is not associated with an increased risk of uterine leiomyomas in a Japanese population.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Feb 2006
Tsujino Taro, Ohara Noriyuki, Yoshida Shigeki, Kennedy Stephen, Takemura Naoya, Deguchi Masashi, Maruo Takeshi
Abstract excerpt
The CYP17 gene is thought to be a candidate gene for susceptibility to hormone-related diseases. A single (T?C) nucleotide polymorphism in the promoter region of CYP17 is speculated to influence its transcription. The present study was conducted to investigate the possible association between uterine leiomyomas and CYP17 gene polymorphism in a Japanese population. Genotyping analysis of the CYP17 gene was...
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