Article
The -2549 insertion/deletion polymorphism of VEGF gene associated with uterine leiomyoma susceptibility in women from Southeastern Iran.
Ginekologia polska - 1 Jan 2017
Keshavarzi Farshid, Salimi Saeedeh, Mohammadpour-Gharehbagh Abbas, Teimoori Batool, Yazdi Atefeh, Farajian-Mashhadi Farzaneh, Yaghmaei Minoo, Mokhtari Mojgan
Abstract excerpt
OBJECTIVES: Vascular endothelial growth factor (VEGF) is an important angiogenic factor that regulates angiogenesis and mediates sex steroid-induced cell growth. The present study investigated the association of VEGF gene-2578C/A (rs699947) and -2549 insertion/deletion polymorphisms in the promoter region of VEGF-A gene and uterine leiomyoma susceptibility in Southeast of Iran. MATERIAL AND METHODS: One hundred...
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