Article
Dynamin: functional design of a membrane fission catalyst.
Annual review of cell and developmental biology - 1 Jan 2011
Schmid Sandra L, Frolov Vadim A
Abstract excerpt
Dynamin, best studied for its role in clathrin-mediated endocytosis, is the prototypical member of a family of multidomain GTPases involved in fission and remodeling of multiple organelles. Recent studies have shown that dynamin alone can catalyze fission of membrane tubules and vesicle formation from planar lipid templates. Thus, dynamin appears to be a self-sufficient fission machine. Here we review the...
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