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Article

GRK5 Is Associated with the Regulation of Methadone Dosage in Heroin Dependence.

The international journal of neuropsychopharmacology - 1 Oct 2018

Wang Sheng-Chang, Chung Ren-Hua, Kuo Hsiang-Wei, Liu Tung-Hsia, Fang Chiu-Ping, Liu Shu Chih, Liu Chia-Chen, Tsou Hsiao-Hui, Chen Andrew C H, Liu Yu-Li

Abstract excerpt

Background: There is no countable biomarker for opioid dependence treatment responses thus far. In this study, we recruited Taiwanese methadone maintenance treatment patients to search for genes involving the regulatory mechanisms of methadone dose by genome-wide association analyses. Methods: A total of 344 Taiwanese methadone maintenance treatment patients were included in a genome-wide association study. The...

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Identifiers

PMID: 30060048
DOI: 10.1093/ijnp/pyy066
PMCID: PMC6165957

Genes

GRK5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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