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Article

Precision therapeutic opioid dosing implications from genetic biomarkers and craving score.

Medicine - 29 May 2020

Chang Hsin-Wen, Ho Wen-Chao, Huang Chieh-Liang, Wang Ruey-Yun

Abstract excerpt

Determining the clinically optimal dose in methadone maintenance therapy (MMT) is a time-consuming procedure, which considers clinical signs and symptoms.To perform a quantitative trait locus association for identifying genetic variants for MMT dosage that underlie heroin addiction and methadone metabolism and then integrate several genotypic and phenotypic factors are potential predictors for clinically optimal...

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Share to Cytochrome P-450 CYP2B6
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 32481444
DOI: 10.1097/MD.0000000000020429

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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