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Article

Association study of genetic polymorphisms in GABRD with treatment response and dose in methadone maintenance treatment.

Personalized medicine - 1 Sept 2021

Xie Xiaohu, Gu Jun, Zhuang Dingding, Chen Xiaoyu, Zhou Yun, Shen Wenwen, Li Longhui, Liu Yue, Xu Wenjin, Hong Qingxiao, Chen Weisheng, Zhou Wenhua, Liu Huifen

Abstract excerpt

Aim: This study determined if gene variants in the GABA receptor delta subunit (GABRD) are associated with treatment response and dose in methadone maintenance treatment (MMT) for heroin addiction. Materials & methods: A total of 286 MMT patients were recruited and divided into response and nonresponse groups based on retention time in therapy. A total of 177 responders were classified into low dose and high dose...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34160285
DOI: 10.2217/pme-2021-0063

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