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Article

Several nAChRs gene variants are associated with phenotypes of heroin addiction in Chinese Han population.

Neuroscience letters - 23 Mar 2022

Cai Xintong, Zhang Jianbo, Li Yunxiao, Deji Cuola, Zhou Jinting, Li Shengbin

Abstract excerpt

Heroin addiction is a chronic and complex brain disease. Nicotinic acetylcholine receptors (nAChRs) have been shown as major control points in many of the neurological and physiological disorders involved in heroin addiction. In the present study, thirty-three SNPs across nine nAChR genes were selected and probed for their associations with heroin addiction phenotypes in 801 unrelated northwestern Chinese Han...

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PMID: 35176404
DOI: 10.1016/j.neulet.2022.136532

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