Article
Impact on the Onset of Psychosis of a Polygenic Schizophrenia-Related Risk Score and Changes in White Matter Volume.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2018
Harrisberger Fabienne, Smieskova Renata, Egli Tobias, Simon Andor E, Riecher-Rössler Anita, Fusar-Poli Paolo, Papassotiropoulos Andreas, Borgwardt Stefan
Abstract excerpt
BACKGROUND: Reductions in the volume of brain white matter are a common feature in schizophrenia and bipolar disorder while the association between white matter and polygenic schizophrenia-related risk is unclear. To look at the intermediate state between health and the full-blown disorder, we investigated this aspect in groups of patients before and after the onset of psychosis. METHODS: On a 3 Tesla scanner,...
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