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Polygenic risk score for five major psychiatric disorders associated with volume of distinct brain regions in the general population.

Biological psychology - 1 Mar 2023

Wang Ziyi, Liu Chang, Dong Qi, Xue Gui, Chen Chunhui

Abstract excerpt

Risk genes and abnormal brain structural indices of psychiatric disorders have been extensively studied. However, whether genetic risk influences brain structure in the general population has been rarely studied. The current study enrolled 483 young Chinese adults, calculated their polygenic risk scores (PRS) for psychiatric disorders based on Psychiatric Genomics Consortium GWAS results, and examined the...

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PMID: 36858107
DOI: 10.1016/j.biopsycho.2023.108530

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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