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Article

Schizophrenia polygenic risk score influence on white matter microstructure.

Journal of psychiatric research - 1 Feb 2020

Simões Beatriz, Vassos Evangelos, Shergill Sukhi, McDonald Colm, Toulopoulou Timothea, Kalidindi Sridevi, Kane Fergus, Murray Robin, Bramon Elvira, Ferreira Hugo, Prata Diana

Abstract excerpt

Schizophrenia (SZ) and bipolar disorder (BD) are highly heritable, share symptomatology, and have a polygenic architecture. The impact of recent polygenic risk scores (PRS) for psychosis, which combine multiple genome-wide associated risk variations, should be assessed on heritable brain phenotypes also previously associated with the illnesses, for a better understanding of the pathways to disease. We have...

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Identifiers

PMID: 31770658
DOI: 10.1016/j.jpsychires.2019.11.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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