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Article

Roles of fibronectin isoforms in neonatal vascular development and matrix integrity.

PLoS biology - 1 Jul 2018

Kumra Heena, Sabatier Laetitia, Hassan Amani, Sakai Takao, Mosher Deane F, Brinckmann Jürgen, Reinhardt Dieter P

Abstract excerpt

Fibronectin (FN) exists in two forms-plasma FN (pFN) and cellular FN (cFN). Although the role of FN in embryonic blood vessel development is well established, its function and the contribution of individual isoforms in early postnatal vascular development are poorly understood. Here, we employed a tamoxifen-dependent cFN inducible knockout (cFN iKO) mouse model to study the consequences of postnatal cFN deletion...

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Share to Animals, Newborn
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30036393
DOI: 10.1371/journal.pbio.2004812
PMCID: PMC6072322

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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