Article

Impact of the maternal environment on cardiovascular features of the offspring in a mouse model of Marfan syndrome

2025-09-16

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Marfan syndrome (MFS) is a systemic disorder of the connective tissue caused by heterozygous mutations in the FBN1 gene, which encodes fibrillin 1, a glycoprotein that constitutes elastic fibers. MFS does not exhibit sexual dimorphism regarding prevalence; however, it remains unknown whether the paternal or maternal inheritance of the FBN1 mutation affects the cardiovascul...

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Literature Corpus work: e645ee8d-451c-5b3f-b59c-cc3b7431e5e8
DOI: 10.1101/2025.09.10.675335

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