Elastic and collagenous networks in vascular diseases.

Abstract excerpt

Supravalvular aortic stenosis (SVAS), Marfan syndrome (MFS) and Ehlers-Danlos syndrome type IV (EDS IV) are three clinical entities characterized by vascular abnormalities that result from mutations of structural components of the extracellular matrix (ECM). Analyses of naturally occurring human mutations and of artificially generated deficiencies in the mouse have provided insights into the pathogenesis of these...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Blood Vessels
• Share to Ehlers-Danlos Syndrome
• Share to Elastin