Article
Endothelium-derived fibronectin regulates neonatal vascular morphogenesis in an autocrine fashion.
Angiogenesis - 1 Nov 2017
Turner Christopher J, Badu-Nkansah Kwabena, Hynes Richard O
Abstract excerpt
Fibronectin containing alternatively spliced EIIIA and EIIIB domains is largely absent from mature quiescent vessels in adults, but is highly expressed around blood vessels during developmental and pathological angiogenesis. The precise functions of fibronectin and its splice variants during developmental angiogenesis however remain unclear due to the presence of cardiac, somitic, mesodermal and neural defects in...
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